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Merck
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主要文件

SML0934

Sigma-Aldrich

Enfuvirtide acetate salt

≥95% (HPLC)

别名:

T-20 acetate salt

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About This Item

经验公式(希尔记法):
C204H301N51O64 · xC2H4O2
分子量:
4491.88 (free base basis)
分類程式碼代碼:
51111800
NACRES:
NA.77

品質等級

化驗

≥95% (HPLC)

形狀

powder

儲存條件

desiccated
protect from light

顏色

white to off-white

運輸包裝

wet ice

儲存溫度

−20°C

Amino Acid Sequence

Ac-Tyr-Thr-Ser-Leu-Ile-His-Ser-Leu- Ile-Glu-Glu-Ser-Gln-Asn-Gln-Gln-Glu- Lys-Asn-Glu-Gln-Glu-Leu-Leu-Glu- Leu-Asp-Lys-Trp-Ala-Ser-Leu-Trp-Asn-Trp-Phe-NH2 acetate

一般說明

Enfuvirtide acetate salt is a linear synthetic peptide made of 36 amino acids. It has an acetylated N-terminus and a carboxamide C-terminus. Enfuvirtide is catabolized with the help of proteolytic enzymes.

生化/生理作用

Enfuvirtide is an HIV fusion inhibitor used to patients with multi-drug resistant HIV. Enfuvirtide binds to gp41 preventing the creation of an entry pore for the HIV-1 virus.

其他說明

Light sensitive

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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访问文档库

Desk Encyclopedia of Microbiology (2010)
Alexander Herrmann et al.
Scientific reports, 10(1), 1326-1326 (2020-01-30)
Overcoming the global health threat of HIV infection requires continuous pipelines of novel drug candidates. We identified the γ-pyrone polyketides Aureothin/Neoaureothin as potent hits by anti-HIV screening of an extensive natural compound collection. Total synthesis of a structurally diverse group

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