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About This Item
经验公式(希尔记法):
C14H9Cl2N3O
CAS号:
分子量:
306.15
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
DMSO: 15 mg/mL (clear solution)
储存温度
2-8°C
SMILES字符串
Clc1cccc(C(=O)Nc2cnc3[nH]ccc3c2)c1Cl
InChI
1S/C14H9Cl2N3O/c15-11-3-1-2-10(12(11)16)14(20)19-9-6-8-4-5-17-13(8)18-7-9/h1-7H,(H,17,18)(H,19,20)
InChI key
SIMLBFHHXAMGGM-UHFFFAOYSA-N
生化/生理作用
AZ513 is a reversible, noncompetitive FAAH inhibitor.
AZ513 is a reversible, noncompetitive FAAH inhibitor. It also binds non-competitively at a site distinct from the catalytic site. AZ513 is 20-fold more potent against rat FAAH (IC50 27 nM) than the human form (IC50 551 nM).
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