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化驗
≥98% (HPLC)
形狀
powder
儲存條件
desiccated
顏色
white to tan
溶解度
H2O: ≥15 mg/mL at ~60 °C
儲存溫度
−20°C
SMILES 字串
Cl.CC(=O)O[C@H]1CN2CC[C@H]1CC2
InChI
1S/C9H15NO2.ClH/c1-7(11)12-9-6-10-4-2-8(9)3-5-10;/h8-9H,2-6H2,1H3;1H/t9-;/m0./s1
InChI 密鑰
LWWSARSTZGNKGV-FVGYRXGTSA-N
應用
Aceclidine hydrochloride may be used in muscarinic acetylcholine receptor-mediated cell signaling studies.
生化/生理作用
Aceclidine at a concentration of 5 and 50 μg is capable of enhancing the outflow facility, following ciliary muscle disinsertion.
Aceclidine hydrochloride is a parasympathomimetic drug with weak anticholinesterase activity. It acts on cholinergic nerve-endings, lowers intraocular pressure and potent therapeutic agent for open-angle glaucoma.
Aceclidine is a non-selective muscarinic acetylcholine receptor partial agonist that is effective in reducing intraocular pressure.
特點和優勢
This compound is featured on the Acetylcholine Receptors (Muscarinic) page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
訊號詞
Danger
危險聲明
危險分類
Acute Tox. 3 Dermal - Acute Tox. 3 Oral
儲存類別代碼
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
水污染物質分類(WGK)
WGK 3
閃點(°F)
Not applicable
閃點(°C)
Not applicable
其他客户在看
Aceclidine effects on outflow facility after ciliary muscle disinsertion
Ophthalmologica, 210(5), 303-307 (1996)
Double-blind cross-over comparison of aceclidine and pilocarpine in open-angle glaucoma.
The British journal of ophthalmology, 54(8), 510-521 (1970-08-01)
商品
Muscarinic acetylcholine receptors mediate acetylcholine actions in CNS and non-nervous tissues, crucial for cell signaling.
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