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![4-{[(4-METHYLPHENYL)SULFONYL]OXY}BUTYL 4-METHYLBENZENESULFONATE AldrichCPR](/deepweb/assets/sigmaaldrich/product/structures/208/494/a5122b67-8573-4730-83f8-8a65b4e244a2/640/a5122b67-8573-4730-83f8-8a65b4e244a2.png)
化驗
≥98% (HPLC)
形狀
powder
drug control
psicótropo (Spain); Decreto Lei 15/93: Tabela IV (Portugal)
顏色
off-white to light brown
溶解度
H2O: ≥5 mg/mL at 60 °C
儲存溫度
2-8°C
InChI
1S/C16H23NO.ClH/c1-3-6-15(17-11-4-5-12-17)16(18)14-9-7-13(2)8-10-14;/h7-10,15H,3-6,11-12H2,1-2H3;1H
InChI 密鑰
MWRACNBZNVAJHE-UHFFFAOYSA-N
應用
Pyrovalerone hydrochloride may be used in dopamine-mediated cell signaling studies.
生化／生理作用
Pyrovalerone hydrochloride is a CNS Stimulant; norepinephrine-dopamine reuptake inhibitor (NDRI)
Pyrovalerone hydrochloride is a rapidly-absorbed psychostimulant. It belongs to the class of synthetic cathinones often used as performance-enhancing agent by athletes before being banned.
Pyrovalerone is a norepinephrine-dopamine reuptake inhibitor (NDRI) that acts as a CNS stimulant.
特點和優勢
This compound is featured on the Dopamine Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
訊號詞
Warning
危險聲明
危險分類
Acute Tox. 4 Oral - STOT SE 3
標靶器官
Central nervous system
儲存類別代碼
11 - Combustible Solids
水污染物質分類（WGK）
WGK 3
閃點（°F）
Not applicable
閃點（°C）
Not applicable
历史批次信息供参考:
Peter C Meltzer et al.
Journal of medicinal chemistry, 49(4), 1420-1432 (2006-02-17)
Dopamine, serotonin, and norepinephrine are essential for neurotransmission in the mammalian system. These three neurotransmitters have been the focus of considerable research because the modulation of their production and their interaction at monoamine receptors has profound effects upon a multitude
Jane M Prosser et al.
Journal of medical toxicology : official journal of the American College of Medical Toxicology, 8(1), 33-42 (2011-11-24)
Synthetic cathinones have recently emerged and grown to be popular drugs of abuse. Their dramatic increase has resulted in part from sensationalized media attention as well as widespread availability on the Internet. They are often considered "legal highs" and sold
H S Shin et al.
Journal of analytical toxicology, 20(7), 568-572 (1996-11-01)
Detection and identification of pyrovalerone and its metabolite, a hydroxylated product, are described. Their identities were confirmed by comparing their mass spectra and gas chromatographic retention times with those of the synthetic standards. The analytical method of pyrovalerone and its
Sabina Strano-Rossi et al.
Rapid communications in mass spectrometry : RCM, 24(18), 2706-2714 (2010-09-04)
A method for the toxicological screening of the new designer drug methylenedioxypyrovalerone (MDPV) is described; with an emphasis on its application for anti-doping analysis. The metabolism of MDPV was evaluated in vitro using human liver microsomes and S9 cellular fractions
The metabolism of pyrovalerone hydrochloride.
W Michaelis et al.
Journal of medicinal chemistry, 13(3), 497-503 (1970-05-01)
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