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Merck

SML0051

Sigma-Aldrich

白藜芦醇三甲醚

≥98% (HPLC)

别名:

1,3-dimethoxy-5-[(1E)-2-(4-methoxyphenyl)ethenyl]-benzene; Tri-O-methylresveratrol; Trimethoxy-trans-stilbene

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About This Item

经验公式(希尔记法):
C17H18O3
CAS号:
分子量:
270.32
分類程式碼代碼:
12352200

化驗

≥98% (HPLC)

形狀

powder

顏色

white to tan

溶解度

DMSO: ≥34 mg/mL

運輸包裝

wet ice

儲存溫度

−20°C

應用

E-Resveratrol Trimethyl Ether was used to study the effect of trans- and cis-stilbene polyphenols on mitochondrial clustering and p53-dependent apoptosis of cancer cells.

生化/生理作用

E-Resveratrol Trimethyl Ether inhibits the activation of SAPK/c-Jun N-terminal kinase (JNK), and reduces the levels of NF-κB and AP-1 in the nucleus. It acts as anti-migratory, anti-adhesive and anti-invasive agent.
E-Resveratrol Trimethyl Ether is a Resveratrol analog, SIRT activator
E-Resveratrol Trimethyl Ether, also known as trimethoxy-trans-stilbene, has been shown to inhibit migration and invasion of tumor cell lines such as HepG2 and A549 by a mechanism that involves the reduction of matrix metalloproteinase (MMP) expression.

訊號詞

Danger

危險分類

Aquatic Acute 1 - Aquatic Chronic 1 - Eye Dam. 1 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Ya-Ting Yang et al.
Molecular nutrition & food research, 53(3), 407-416 (2008-12-17)
Resveratrol (3,5,4'-trihydroxystilbene) is a natural polyphenol that presents various physiological activities. It has been reported that the methylated derivatives of resveratrol show better potential antifungal and antiproliferative activities than resveratrol. In the present study, we investigated the inhibitory effect of
Alexander Gosslau et al.
European journal of pharmacology, 587(1-3), 25-34 (2008-05-20)
We previously reported that 3,4,5,4'-tetramethoxy-trans-stilbene (MR-4) induces p53 and perinuclear mitochondrial clustering in cancer cells [Gosslau, A., Chen, M., Ho, C.-T., Chen, K.Y., 2005, A methoxy derivative of resveratrol analogue selectively induced activation of the mitochondrial apoptotic pathway in transformed

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