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Merck

SMB00081

Sigma-Aldrich

Wogonoside

≥95% (LC/MS-ELSD)

别名:

5,7-Dihydroxy 8-methoxyflavone 7-glucuronide, Glychionide B, Oroxindin, Wogonin 7-glucuronide

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About This Item

经验公式(希尔记法):
C22H20O11
CAS号:
分子量:
460.39
MDL號碼:
分類程式碼代碼:
12352205
PubChem物質ID:
NACRES:
NA.25

化驗

≥95% (LC/MS-ELSD)

形狀

solid

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

−20°C

SMILES 字串

COc1c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc(O)c3C(=O)C=C(Oc13)c4ccccc4

InChI

1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1

InChI 密鑰

LNOHXHDWGCMVCO-NTKSAMNMSA-N

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一般說明

Natural product derived from plant source.

生化/生理作用

Wogonoside, a flavanoid, is known for its anti-inflammatory properties. Wogonoside may have therapeutic potential for use in diseases which involve the development of inflammation and angiogenesis through its inhibition of LPS-induced angiogenesis.

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Yan Yan et al.
Chinese medicine, 13, 54-54 (2018-11-06)
Microbial fermentation has been widely applied in traditional Chinese medicine (TCM) for thousands of years in China. Various beneficial effects of fermentation for applications in TCM or herbals have been reported, such as enhanced anti-ovarian cancer, antioxidative activity, and neuroprotective
R Xiao et al.
Human & experimental toxicology, 36(11), 1169-1176 (2016-12-13)
Wogonoside is the main flavonoid of the traditional Chinese medicinal herb Scutellaria baicalensis Georgi and has been found to induce growth suppression in myelogenous leukemia cells. However, its activity in T acute lymphoblastic leukemia (T-ALL) is still unclear. In this
Zhenyu Zhu et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878(24), 2184-2190 (2010-07-21)
The aim of this study was to compare the pharmacokinetics of baicalin and wogonoside in rats following oral administration of Xiaochaihu Tang (Minor Radix Bupleuri Decoction) and Radix scutellariae extract. Thus, a specific LC-MS method was developed and validated for
Xiao-Yan Wei et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 1061-1062, 248-255 (2017-08-02)
A rapid, sensitive, and selective UPLC-TQ-MS/MS method was established and validated for the determination and pharmacokinetic investigation of rhein, coptisine, berberine, palmatine, baicalin and wogonoside from Sanhuang Xiexin Decoction (SXD) extracts. A Waters BEH C
Ying Wang et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 877(20-21), 1820-1826 (2009-06-06)
A specific ultra-performance liquid chromatography-mass spectrometry (UPLC-MS) method was developed for the simultaneous determination of puerarin, daidzein, baicalin, wogonoside and liquiritin in rat plasma. Chromatographic separation was performed on a C(18) column packed with 1.7 microm particles by a linear

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