SAE0099

S-(5′-Adenosyl)-L-homocysteine ready made solution

≥98% (HPLC), 1 mg/ml in 0.02 M HCl

• 别名: 5′-Deoxy-S-adenosyl-L-homocysteine, AdoHcy, S-(5′-Deoxyadenosine-5′)-L-homocysteine, SAH
• 分類程式碼代碼: 12352202
• NACRES: NA.51

属性

• 化驗: ≥98% (HPLC)
• 濃度: 1 mg/mL
• 運輸包裝: dry ice
• 儲存溫度: −20°C

说明

一般說明

S-(5′-Adenosyl)-L-homocysteine (SAH) is a compound that occurs biologically as a by-product of reactions which S-adenosyl-L-methionine-dependent methyltransferases catalyze. These enzymes use S-adenosyl-L-methionine (SAM) as the parent material for cellular methyl transfer processes, such as DNA methylation. In its turn, SAH is cleaved by SAH hydrolase to produce homocysteine and adenosine. The homocysteine pathway and the plasma measurement of SAM and SAH3 have been studied in relation to topics such as cancer, nutritional deficiencies, and Alzheimer′s disease. SAH has been used to develop various methyltransferase activity assays, such as the following:

• Multiwell plate assay for protein methyltransferase SET7/9 activity
• Fluorescence polarization (FP) assay
• HPLC assay coupled to fluorometric detection

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable