推荐产品
产品名称
Anti-Dystrophin Antibody, clone 10G10K7, Rabbit Monoclonal,
生物来源
rabbit
质量水平
物料
colorless
克隆
10G10K7, monoclonal
表单
liquid
种属反应性
mouse, rat
浓度
0.5mg/mL
技术
immunofluorescence: 1:50 - 1:200
immunohistochemistry: 1:50 - 1:200
颜色
colorless
同位素/亚型
IgG
免疫原序列
LESQLHRLRQLLEQPQAEAKVNGTTVSSPSTSLQRSDSSQPMLLRVVGSQTSDSMGEEDLLSPPQDTSTGLEEVMEQLNNSFPSSRGRNTPGKPMREDTM
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... DMD(1756)
一般描述
This gene spans a genomic range of greater than 2 Mb and encodes a large protein containing an N-terminal actin-binding domain and multiple spectrin repeats. The encoded protein forms a component of the dystrophin-glycoprotein complex (DGC), which bridges the inner cytoskeleton and the extracellular matrix. Deletions, duplications, and point mutations at this gene locus may cause Duchenne muscular dystrophy (DMD), Becker muscular dystrophy (BMD), or cardiomyopathy. Alternative promoter usage and alternative splicing result in numerous distinct transcript variants and protein isoforms for this gene. [provided by RefSeq, Dec 2016]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 3586-3685 of human Dystrophin (P11532).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
应用
IHC, IF/ICC
储存分类代码
10 - Combustible liquids
WGK
WGK 1
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