SAB5702738

Anti-LIN28A Antibody, clone 2S1I10, Rabbit Monoclonal

• 别名: CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 2S1I10, monoclonal
• 表单: liquid
• 分子量: 26 kDa
• 种属反应性: human, rat, rat
• 浓度: 0.70 mg/mL
• 技术: immunofluorescence: 1:50 - 1:200; western blot: 1:10000 - 1:20000
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTARAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKS
• UniProt登记号: Q9H9Z2
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... LIN28A(79727)

说明

一般描述

This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRNAs and by disrupting the maturation of certain miRNAs involved in embryonic development. This protein prevents the terminal processing of the LET7 family of microRNAs which are major regulators of cellular growth and differentiation. Aberrant expression of this gene is associated with cancer progression in multiple tissues. [provided by RefSeq, Sep 2015]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human LIN28A (Q9H9Z2).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB, IF/ICC

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1