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Merck

SAB5702618

Sigma-Aldrich

Anti-ACTN2 Antibody, clone 2P7E6, Rabbit Monoclonal

别名:

CMD1AA, CMH23

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.46

生物源

rabbit

品質等級

材料

colorless

無性繁殖

2P7E6, monoclonal

形狀

liquid

分子量

104 kDa

物種活性

rat, human, rat

濃度

0.34 mg/mL

技術

immunofluorescence: 1:50 - 1:200
western blot: 1:500 - 1:2000

顏色

colorless

同型

IgG

免疫原序列

MNQIEPGVQYNYVYDEDEYMIQEEEWDRDLLLDPAWEKQQRKTFTAWCNSHLRKAGTQIENIEEDFRNGLKLMLLLEVISGERLPKPDRGKMRFHKIANV

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... ACTN2(88)

一般說明

Alpha actinins belong to the spectrin gene superfamily which represents a diverse group of cytoskeletal proteins, including the alpha and beta spectrins and dystrophins. Alpha actinin is an actin-binding protein with multiple roles in different cell types. In nonmuscle cells, the cytoskeletal isoform is found along microfilament bundles and adherens-type junctions, where it is involved in binding actin to the membrane. In contrast, skeletal, cardiac, and smooth muscle isoforms are localized to the Z-disc and analogous dense bodies, where they help anchor the myofibrillar actin filaments. This gene encodes a muscle-specific, alpha actinin isoform that is expressed in both skeletal and cardiac muscles. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ACTN2 (P35609).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

應用

WB, IF/ICC

儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1


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