生物源
rabbit
品質等級
材料
colorless
無性繁殖
4X6E1, monoclonal
形狀
liquid
分子量
28 kDa
物種活性
human, rat, rat
濃度
0.2 mg/mL
技術
western blot: 1:500 - 1:2000
顏色
colorless
同型
IgG
免疫原序列
MDDREDLVYQAKLAEQAERYDEMVESMKKVAGMDVELTVEERNLLSVAYKNVIGARRASWRIISSIEQKEENKGGEDKLKMIREYRQMVETELKLICCDI
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... YWHAE(7531)
一般說明
This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the mouse ortholog. It interacts with CDC25 phosphatases, RAF1 and IRS1 proteins, suggesting its role in diverse biochemical activities related to signal transduction, such as cell division and regulation of insulin sensitivity. It has also been implicated in the pathogenesis of small cell lung cancer. Two transcript variants, one protein-coding and the other non-protein-coding, have been found for this gene. [provided by RefSeq, Aug 2008]
免疫原
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human 14-3-3 epsilon (P62258).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
應用
WB
儲存類別代碼
10 - Combustible liquids
水污染物質分類(WGK)
WGK 1
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