SAB5702285

Anti-MRP1/ABCC1 Antibody, clone 0J6M2, Rabbit Monoclonal

• 别名: ABC29, ABCC, GS-X, MRP, MRP1
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 0J6M2, monoclonal
• 表单: liquid
• 分子量: 200-250 kDa
• 种属反应性: human, rat, rat
• 浓度: 1.00 mg/mL
• 技术: immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:1000
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: ESSASFLSRITFWWITGLIVRGYRQPLEGSDLWSLNKEDTSEQVVPVLVKNWKKECAKTRKQPVKVVYSSKDPAQPKESSKVDANEEVEALIVKS
• UniProt登记号: P33527
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... ABCC1(4363)

说明

一般描述

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown. [provided by RefSeq, Apr 2012]

免疫原

PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.

Recombinant fusion protein containing a sequence corresponding to amino acids 210-304 of human MRP1/ABCC1 (NP_004987.2).

应用

WB, IHC

安全信息

• 象形图: GHS07,GHS09
• 警示用语：: Warning
• 危险声明: H317,H411
• 预防措施声明: P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313
• 危险分类: Aquatic Chronic 2 - Skin Sens. 1
• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 3