SAB5702040

Anti-Aromatase (CYP19A1) Antibody, clone 5C5N7, Rabbit Monoclonal

• 别名: ARO, ARO1, CPV1, CYAR, CYP19, CYPXIX, P-450AROM
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 5C5N7, monoclonal
• 表单: liquid
• 分子量: 58 kDa
• 种属反应性: human
• 浓度: 1.75 mg/mL
• 技术: immunofluorescence: 1:50 - 1:200; immunohistochemistry: 1:50 - 1:200; western blot: 1:500 - 1:2000
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: MVLEMLNPIHYNITSIVPEAMPAATMPVLLLTGLFLLVWNYEGTSSIPGPGYCMGIGPLISHGRFLWMGIGSACNYYNRVYGEFMRVWISGEETLIISKS
• UniProt登记号: P11511
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... CYP19A1(1588)

说明

一般描述

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and catalyzes the last steps of estrogen biosynthesis. Mutations in this gene can result in either increased or decreased aromatase activity; the associated phenotypes suggest that estrogen functions both as a sex steroid hormone and in growth or differentiation. Alternative promoter use and alternative splicing results in multiple transcript variants that have different tissue specificities. [provided by RefSeq, Dec 2016]

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Aromatase (CYP19A1) (P11511).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB, IHC, IF/ICC

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1