SAB5701997

Anti-HFE Antibody, clone 2O7D2, Rabbit Monoclonal

• 别名: HFE, HFE1, HH, HLA-H, MVCD7, TFQTL2, hemochromatosis
• UNSPSC代码: 12352203
• NACRES: NA.46

属性

• 生物来源: rabbit
• 质量水平: 100
• 物料: colorless
• 克隆: 2O7D2, monoclonal
• 表单: liquid
• 分子量: 45 kDa
• 种属反应性: human
• 浓度: 0.60 mg/mL
• 技术: western blot: 1:500 - 1:2000
• 颜色: colorless
• 同位素/亚型: IgG
• 免疫原序列: KEFEPKDVLPNGDGTYQGWITLAVPPGEEQRYTCQVEHPGLDQPLIVIWEPSPSGTLVIGVISGIAVFVVILFIGILFIILRKRQGSRGAMGHYVLAERE
• UniProt登记号: Q30201
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... HFE(3077)

说明

一般描述

The protein encoded by this gene is a membrane protein that is similar to MHC class I-type proteins and associates with beta2-microglobulin (beta2M). It is thought that this protein functions to regulate iron absorption by regulating the interaction of the transferrin receptor with transferrin. The iron storage disorder, hereditary haemochromatosis, is a recessive genetic disorder that results from defects in this gene. At least nine alternatively spliced variants have been described for this gene. Additional variants have been found but their full-length nature has not been determined.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 249-348 of human HFE (Q30201).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

应用

WB

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1