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Merck
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Key Documents

SAB5701201

Sigma-Aldrich

Anti-SHP2 antibody produced in rabbit

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

抗體產品種類

primary antibodies

無性繁殖

monoclonal

形狀

liquid

物種活性

mouse, rat, human

濃度

0.77 mg/mL

技術

immunohistochemistry: 1:50-1:200
western blot: 1:500-1:2000

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... PTPN11(5781)

一般說明

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in this gene are a cause of Noonan syndrome as well as acute myeloid leukemia. [provided by RefSeq, Aug 2016]

免疫原

A synthesized peptide derived from human SHP2

外觀

Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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