SAB5701135

Anti- SAV1 antibody produced in rabbit

• UNSPSC代码: 12352203
• NACRES: NA.43

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: liquid
• 种属反应性: rat, human, mouse
• 浓度: 0.65 mg/mL
• 技术: immunohistochemistry: 1:50-1:200; western blot: 1:500-1:2000
• UniProt登记号: Q9H4B6
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... SAV1(60485)

说明

一般描述

WW domain-containing proteins are found in all eukaryotes and play an important role in the regulation of a wide variety of cellular functions such as protein degradation, transcription, and RNA splicing. This gene encodes a protein with two WW domains, a SARAH domain, and a coiled-coil region and is ubiquitously expressed in adult tissues. This protein binds to MST1 (mammalian sterile 20-like kinase 1) and promotes MST1-induced apoptosis. It has also been shown to bind to HAX1 (hematopoietic cell-specific protein 1 (HS1)-associated protein X-1) and to attenuate the anti-apoptotic effects of HAX1. Studies in human and mouse suggest this gene acts as a tumor suppressor.

免疫原

Recombinant protein of human SAV1.

外形

Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable