SAB5700581

Anti-Phospho-CSF1R-Y723 antibody produced in rabbit

• 别名: BANDDOS, C-FMS, CD115, CSF-1R, CSF1R, CSFR, FIM2, FMS, HDLS, M-CSF-R
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: 107; 33
• 种属反应性: human
• 浓度: 0.76mg/ml
• 技术: western blot: 1:500-1:2000
• UniProt登记号: P07333
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: phosphorylation (pTyr723)
• 基因信息: human ... CSF1R(1436)

说明

一般描述

The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma.

免疫原

A phospho synthetic peptide corresponding to residues surrounding Y723 of human CSF1R.

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable