SAB5700412

Anti-Phospho-RB1-S608 antibody produced in rabbit

• 别名: OSRC, PPP1R130, RB, RB1, Rb, p105-Rb, pRb, pp110
• UNSPSC代码: 12352203
• NACRES: NA.43

属性

• 生物来源: rabbit
• 质量水平: 100
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: 106
• 种属反应性: human
• 浓度: 6.29 mg/ml
• 技术: western blot: 1:500-1:2000
• UniProt登记号: P06400
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: phosphorylation (pSer608)
• 基因信息: human ... RB1(5925)

说明

一般描述

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

免疫原

A synthetic phosphorylated peptide around S608 of human RB1 (NP_000312.2).

外形

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

储存及稳定性

Store at -20℃. Avoid freeze / thaw cycles.

安全信息

• 储存分类代码: 12 - Non Combustible Liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable