SAB5700103

Anti-MAP2K2/MEK2 Antibody

rabbit polyclonal

• 别名: CFC4, MAP2K2, MAPKK2, MEK2, MKK2, PRKMK2
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 产品名称: Anti-MAP2K2 antibody produced in rabbit,
• 生物源: rabbit
• 品質等級: 100
• 抗體表格: affinity isolated antibody
• 抗體產品種類: primary antibodies
• 無性繁殖: polyclonal
• 形狀: buffered aqueous solution
• 分子量: 44
• 物種活性: rat, human, mouse
• 濃度: 2.41 mg/ml
• 技術: immunohistochemistry: 1:100-1:200; western blot: 1:500-1:2000
• UniProt登錄號: P36507
• 運輸包裝: wet ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... MAP2K2(5605)

说明

一般說明

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is known to play a critical role in mitogen growth factor signal transduction. It phosphorylates and thus activates MAPK1/ERK2 and MAPK2/ERK3. The activation of this kinase itself is dependent on the Ser/Thr phosphorylation by MAP kinase kinase kinases. Mutations in this gene cause cardiofaciocutaneous syndrome (CFC syndrome), a disease characterized by heart defects, mental retardation, and distinctive facial features similar to those found in Noonan syndrome. The inhibition or degradation of this kinase is also found to be involved in the pathogenesis of Yersinia and anthrax. A pseudogene, which is located on chromosome 7, has been identified for this gene.

免疫原

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human MAP2K2 (NP_109587.1).

外觀

PBS with 0.02% sodium azide,50% glycerol,pH7.3.

儲存和穩定性

Store at -20℃. Avoid freeze / thaw cycles.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable