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Key Documents

SAB4702145

Monoclonal Anti-CD36 APC-Cyanine7 produced in mouse

new

别名:

FAT, GPIIIb, GPIV, PAS-4, PASIV, Thrombospondin receptor

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About This Item

分類程式碼代碼:
12352203

共軛

APC-Cy7 conjugate

品質等級

抗體產品種類

primary antibodies

無性繁殖

TR9, monoclonal

形狀

buffered aqueous solution

物種活性

human

技術

flow cytometry: suitable

同型

IgG1

UniProt登錄號

儲存溫度

2-8°C

目標翻譯後修改

unmodified

基因資訊

human ... CD36(948)

一般說明

CD36 (fatty acid translocase, FAT) is an 88 kDa ditopic glycosylated protein that belongs to the class B family of scavenger receptors. CD36 is expressed by most resting marginal zone B cells but not by follicular and B1 B cells, and it is rapidly induced on follicular B cells in vitro upon TLR and CD40 stimulation. CD36 does not affect the development of B cells, but modulates both primary and secondary antibody response. Similarly to glucose transporter GLUT4, CD36 is translocated from intracellular pools to the plasma membrane following cell stimulation by insulin. In mouse, CD36 is responsible for gustatory perception of long-chain fatty acids.

特異性

The antibody TR9 reacts with an extracellular epitope of CD36 (GPIIIb), a 85 kDa integral membrane glycoprotein expressed on platelets, macrophages, endothelial cells, early erythroid cells and megakaryocytes. The antibody TR9 cross-blocks binding of FITC-labeled standard antibody OKM5. Anti-CD36 antibodies inhibit adhesive functions (e.g. adherence of infected erythrocytes to target cells).

免疫原

Platelets

外觀

Stabilizing phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

準備報告

Purified antibody is conjugated with activated tandem dye of allophycocyanin-cyanine 7 (APC-Cy7) under optimum conditions and unconjugated antibody and free fluorochrome are removed by size-exclusion chromatography.

儲存和穩定性

Store at 2-8°C. Protect from prolonged exposure to light. Do not freeze.

其他說明

The antibody solution should be gently mixed before use.

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儲存類別代碼

12 - Non Combustible Liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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