SAB4702104

Monoclonal Anti-CD271, purified produced in mouse

• 别名: NGFR, TNFRSF16, p75NGFR, p75NTR
• 分類程式碼代碼: 12352203

属性

• 共軛: unconjugated
• 品質等級: 100
• 抗體產品種類: primary antibodies
• 無性繁殖: NGFR5, monoclonal
• 形狀: buffered aqueous solution
• 物種活性: human, ( Non-human primates), ( Rabbit), ( Cat)
• 濃度: 1 mg/ml
• 技術: flow cytometry: suitable; immunocytochemistry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable; western blot: suitable
• 同型: IgG1
• UniProt登錄號: P08138
• 儲存溫度: 2-8°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... NGFR(4804)

说明

一般說明

CD271 / NGFR, also known as p75NGFR or p75NTR, is a 75 kDa low affinity receptor for the NGF (nerve growth factor), BDNF (brain-derived growth factor), and other neurotrophins, such as NT3 and NT4/5. Unlike other members of the tumor necrosis factor receptor superfamily of transmembrane proteins, CD271 has unique intracellular domain structure (lacks catalytic activity) and downstream signaling partners. Triggered by its ligands CD271 affects growth, differentiation, migration and death of the nervous system cells.

特異性

The mouse monoclonal antibody NGFR5 (originally C34C) recognizes an epitope within ammino acids 1 - 160 of CD271/NGFR, a 75 kDa transmembrane glycoprotein of the TNFR superfamily.

免疫原

Purified CD271 protein isolated from human melanoma cell line A875

外觀

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

準備報告

Purified by protein-A affinity chromatography.

儲存和穩定性

Store at 2-8°C. Do not freeze.

其他說明

The antibody solution should be gently mixed before use.

安全信息

• 儲存類別代碼: 12 - Non Combustible Liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable