生物来源
hamster
偶联物
unconjugated
抗体形式
purified immunoglobulin
抗体产品类型
primary antibodies
克隆
145-2C11, monoclonal
表单
buffered aqueous solution
种属反应性
mouse
浓度
1 mg/mL
技术
flow cytometry: suitable
同位素/亚型
IgG
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
2-8°C
基因信息
mouse ... Cd3e(12501)
一般描述
The hamster monoclonal antibody 145-2C11 reacts with mouse CD3 (epsilon subunit). This antibody is commonly used as a phenotypic marker for mouse T cells.
免疫原
Mouse BM10-37 cytotoxic T lymphocytes
应用
The reagent is designed for Flow Cytometry analysis using 1-2 μg reagent / 1e6 cells in a suspension.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Solution in phosphate buffered saline, pH 7.4, with 15 mM sodium azide.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
12 - Non Combustible Liquids
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Lisa A Pitcher et al.
European journal of immunology, 35(12), 3643-3654 (2005-11-01)
T cell receptor (TCR) signal transduction is mediated by the immunoreceptor tyrosine-based activation motifs (ITAM). The ten ITAM in the TCR complex are distributed in two distinct signaling modules termed TCR zetazeta and CD3 gammaepsilon/deltaepsilon. To delineate the specific role
Susanne M A Lens et al.
Molecular and cellular biology, 22(15), 5419-5433 (2002-07-09)
The caspase 8 inhibitor c-FLIP(L) can act in vitro as a molecular switch between cell death and growth signals transmitted by the death receptor Fas (CD95). To elucidate its function in vivo, transgenic mice were generated that overexpress c-FLIP(L) in
Qizhi Tang et al.
Journal of immunology (Baltimore, Md. : 1950), 168(9), 4480-4487 (2002-04-24)
FcR nonbinding anti-CD3 epsilon mAbs elicit partial TCR signaling that leads to T cell unresponsiveness and tolerance in vivo. In this study, the membrane-proximal events that promote T cell inactivation by FcR nonbinding anti-CD3 mAbs were examined. In the context
Lingqiao Zhu et al.
Journal of immunology (Baltimore, Md. : 1950), 191(2), 737-744 (2013-06-19)
MHC class II-expressing thymocytes can efficiently mediate positive selection of CD4 T cells in mice. Thymocyte-selected CD4 (T-CD4) T cells have an innate-like phenotype similar to invariant NKT cells. To investigate the development and function of T-CD4 T cells in-depth
Joshua C Cyktor et al.
Infection and immunity, 81(4), 1090-1099 (2013-01-24)
The expression of T cell differentiation markers is known to increase during Mycobacterium tuberculosis infection, and yet the biological role of such markers remains unclear. We examined the requirement of the T cell differentiation marker killer cell lectin-like receptor G1
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