生物来源
rabbit
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 16 kDa
种属反应性
rat, human, mouse
浓度
~1 mg/mL
技术
ELISA: 1:1000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
phosphorylation (pThr34)
基因信息
human ... BIRC5(332)
一般描述
Survivin is also termed as BIRC5 (baculoviral inhibitor of apoptosis repeat-containing 5). It is a multifunctional protein. It belongs to the inhibitor of apoptosis protein (IAP) family. BIRC5 is expressed in fetal tissues and several human malignancies like melanoma. Survivin is located on human chromosome 17q25.
免疫原
The antiserum was produced against synthesized peptide derived from human Survivin around the phosphorylation site of Thr34.
Immunogen Range: 11-60
Immunogen Range: 11-60
生化/生理作用
Survivin/BIRC5 (baculoviral inhibitor of apoptosis repeat-containing 5) plays a major role in ATL (adult T-cell leukemia/lymphoma) cell viability. It can block apoptosis and induce the multiplication of cell. BIRC5 also plays a major role in the development of cancer.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
未找到合适的产品？
试试我们的产品选型工具.
储存分类代码
10 - Combustible liquids
WGK
WGK 1
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Functional polymorphism -31C/G in the promoter of BIRC5 gene and risk of nasopharyngeal carcinoma among chinese.
Ma F, et al.
PLoS ONE, 6(2), e16748-e16748 (2011)
Correlation of local and systemic expression of survivin with histopathological parameters of cutaneous melanoma.
Jovic M, et al.
Vojnosanitetski Pregled. Military-medical and Pharmaceutical Review, 73(11), 1022-1029 (2016)
Gene expression profiling of ATL patients: compilation of disease-related genes and evidence for TCF4 involvement in BIRC5 gene expression and cell viability.
Pise-Masison CA, et al.
Blood, 113(17), 4016-4026 (2009)
Expression analysis of mitotic spindle checkpoint genes in breast carcinoma: role of NDC80/HEC1 in early breast tumorigenicity, and a two-gene signature for aneuploidy.
Bieche I, et al.
Molecular Cancer, 10(1), 23-23 (2011)
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持