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生物源
rabbit
品質等級
共軛
unconjugated
抗體表格
affinity isolated antibody
抗體產品種類
primary antibodies
無性繁殖
polyclonal
形狀
buffered aqueous solution
分子量
antigen 35 kDa
物種活性
human
濃度
~1 mg/mL
技術
ELISA: 1:20000
immunofluorescence: 1:100-1:500
western blot: 1:500-1:1000
NCBI登錄號
UniProt登錄號
運輸包裝
wet ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... OR1D2(4991)
一般說明
Anti-OR1D2 antibody detects endogenous levels of total OR1D2 protein.
The OR1D2 (olfactory receptor family 1 subfamily D member 2) gene is located on human chromosome 17p13.3. The gene is considered as the first olfactory receptor expressed in the nose. It is also found to be expressed in spermatozoa. The encoded protein is a member of G protein-coupled receptor superfamily and exists as a homo-oligomer.
免疫原
The antiserum was produced against synthesized peptide derived from human OR1D2.
Immunogen Range: 201-250
Immunogen Range: 201-250
生化／生理作用
The protein encoded by OR1D2 (olfactory receptor family 1 subfamily D member 2) gene takes part in the process of fertilization by mediating the communication between the sperm and egg via chemotaxis. Sperm expressing OR1D2 is known to migrate toward odorant ligands such as lilial, floralozone and bourgeonal.
特點和優勢
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外觀
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免責聲明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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儲存類別代碼
10 - Combustible liquids
水污染物質分類（WGK）
nwg
閃點（°F）
Not applicable
閃點（°C）
Not applicable
G Ottaviano et al.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 270(12), 3079-3086 (2013-03-26)
Olfactory receptor (OR) expression is also present in the sperm cells and could mediate sperm chemotaxis. OR1D2 was the first OR expressed in the testis demonstrated to be involved in chemotaxis and to be expressed also in the nose with
Marc Spehr et al.
Science (New York, N.Y.), 299(5615), 2054-2058 (2003-03-29)
Although it has been known for some time that olfactory receptors (ORs) reside in spermatozoa, the function of these ORs is unknown. Here, we identified, cloned, and functionally expressed a previously undescribed human testicular OR, hOR17-4. With the use of
Brian L Cook et al.
Proceedings of the National Academy of Sciences of the United States of America, 106(29), 11925-11930 (2009-07-08)
Although understanding of the olfactory system has progressed at the level of downstream receptor signaling and the wiring of olfactory neurons, the system remains poorly understood at the molecular level of the receptors and their interaction with and recognition of
Fallou Wade et al.
The Journal of biological chemistry, 286(17), 15252-15259 (2011-04-02)
G-protein-coupled receptor homo-oligomerization has been increasingly reported. However, little is known regarding the relationship between activation of the receptor and its association/conformational states. The mammalian olfactory receptors (ORs) belong to the G protein-coupled receptor superfamily. In this study, the homo-oligomerization
A partial deletion of the aspartoacylase gene is the cause of Canavan disease in a family from Mexico.
F E Tahmaz et al.
Journal of medical genetics, 38(3), E9-E9 (2001-03-10)
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