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Merck

SAB4501790

Sigma-Aldrich

Anti-LY6E antibody produced in rabbit

affinity isolated antibody

别名:

Ly-6E, Lymphocyte antigen 6E, RIG-E, Retinoic acid-induced gene E protein, Thymic shared antigen 1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 13 kDa

物種活性

human

濃度

~1 mg/mL

技術

ELISA: 1:20000
immunofluorescence: 1:100-1:500

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... LY6E(4061)

一般說明

Anti-LY6E Antibody detects endogenous levels of total LY6E protein.
Anti-LY6E Antibody detects endogenous levels of total LY6E protein. LY6E (lymphocyte antigen 6 family member E) is a glycosylphosphatidylinositol-anchored, interferon (IFN)-inducible protein, that is located on human chromosome 8q24. It is also called as RIG-E.

免疫原

The antiserum was produced against synthesized peptide derived from human LY6E.

Immunogen Range: 17-66

生化/生理作用

LY6E (lymphocyte antigen 6 family member E) controls T lymphocytes proliferation, differentiation and development. It induces HIV-1 Infection. Overexpression of LY6E gene in the peripheral blood cells of individuals with SLE (systemic lupus erythematosus) is associated with lupus activity.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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RIG-E, a human homolog of the murine Ly-6 family, is induced by retinoic acid during the differentiation of acute promyelocytic leukemia cell.
M Mao, et al.
Proceedings of the National Academy of Sciences of the USA, 93(12), 5910-5914 (1996)
Interferon-inducible LY6E Protein Promotes HIV-1 Infection.
Yu J, et al.
Journal of Biochemistry, 292(11), 4674-4685 (2017)
Increased expression of the type I interferon-inducible gene, lymphocyte antigen 6 complex locus E, in peripheral blood cells is predictive of lupus activity in a large cohort of Chinese lupus patients.
J Tang, et al.
Lupus, 17(9), 805-813 (2008)

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