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产品名称
Anti-Integrin β1 antibody produced in rabbit, affinity isolated antibody
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 88 kDa
种属反应性
human, rat, mouse
浓度
~1 mg/mL
技术
ELISA: 1:1000
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
基因信息
human ... ITGB1(3688)
一般描述
Anti-Integrin β1 Antibody detects endogenous levels of total Integrin β1 protein.
Integrin β1 is a mechanosensor, that is located on human chromosome 10p11.22. It is present in normal cells and tumor-associated cells.
免疫原
The antiserum was produced against synthesized peptide derived from human Integrin beta1.
Immunogen Range: 746-795
Immunogen Range: 746-795
应用
Anti-Integrin β1 antibody has been used in western blotting.
生化/生理作用
Integrin β1 acts as an adhesive molecule in the development of de novo focal contact, keratinocyte migration and re-epithelialization of wound tissue.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
β1 Integrin as a Prognostic and Predictive Marker in Triple-Negative Breast Cancer.
Yin HL, et al.
International Journal of Molecular Sciences, 17(9) (2016)
Ggnbp2-Null Mutation in Mice Leads to Male Infertility due to a Defect at the Spermiogenesis Stage.
Liu L,et al.
The American Journal of Pathology, 187(11), 2508-2519 (2017)
Genomic aberrations associated with erlotinib resistance in non-small cell lung cancer cells.
Serizawa M, et al.
Anticancer Research, 33(12), 5223-5233 (2013)
β1 integrin signaling in asymmetric migration of keratinocytes under mechanical stretch in a co-cultured wound repair model.
Lu D, et al.
BioMedical Engineering OnLine, 15(2), 130-130 (2016)
Lingyun Liu et al.
The American journal of pathology, 187(11), 2508-2519 (2017-08-22)
Gametogenetin binding protein 2 (GGNBP2) is an evolutionarily conserved zinc finger protein. Although Ggnbp2-null embryos in the B6 background died because of a defective placenta, 6.8% of Ggnbp2-null mice in the B6/129 mixed background were viable and continued to adulthood.
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