推荐产品
生物来源
rabbit
质量水平
偶联物
unconjugated
抗体形式
affinity isolated antibody
抗体产品类型
primary antibodies
克隆
polyclonal
表单
buffered aqueous solution
分子量
antigen 10 kDa
种属反应性
rat, mouse, human
浓度
~1 mg/mL
技术
ELISA: 1:10000
immunofluorescence: 1:100-1:500
immunohistochemistry: 1:50-1:100
western blot: 1:500-1:1000
NCBI登记号
UniProt登记号
运输
wet ice
储存温度
−20°C
靶向翻译后修饰
unmodified
基因信息
human ... HSPE1(3336)
一般描述
Anti-HSP10 Antibody detects endogenous levels of total HSP10 protein.
HSP10 (heat shock protein family E member 1) is a molecular chaperone protein, located in mitochondria. It is encoded by HSPE1 (heat shock protein family E member 1) gene, that is located on human chromosome 2q33.1.
免疫原
The antiserum was produced against synthesized peptide derived from human HSP10.
Immunogen Range: 51-100
Immunogen Range: 51-100
应用
Anti-HSP10 antibody has been used in microarray and western blotting.
生化/生理作用
Overexpression of HSP10 (heat shock protein family E member 1) protein blocks apoptosis and results in poor prognosis of astrocytoma. It participates in immunomodulation and tumor progression.
特点和优势
Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.
外形
Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
免责声明
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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储存分类代码
10 - Combustible liquids
WGK
nwg
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Effects of muscular dystrophy, exercise and blocking activin receptor IIB ligands on the unfolded protein response and oxidative stress.
Hulmi JJ, et al.
Free Radical Biology & Medicine, 99, 308-322 (2016)
Hsp10 nuclear localization and changes in lung cells response to cigarette smoke suggest novel roles for this chaperonin.
Corrao S, et al.
Open Biology, 4(10) (2014)
Juha J Hulmi et al.
Free radical biology & medicine, 99, 308-322 (2016-10-23)
Protein homeostasis in cells, proteostasis, is maintained through several integrated processes and pathways and its dysregulation may mediate pathology in many diseases including Duchenne muscular dystrophy (DMD). Oxidative stress, heat shock proteins, endoplasmic reticulum (ER) stress and its response, i.e.
Elevated expression of HSP10 protein inhibits apoptosis and associates with poor prognosis of astrocytoma.
Fan W, et al.
PLoS ONE, 12(10) (2017)
Effects of intrinsic aerobic capacity, aging and voluntary running on skeletal muscle sirtuins and heat shock proteins.
Karvinen S, et al.
Experimental Gerontology, 79, 46-54 (2016)
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