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Merck

SAB4501408

Sigma-Aldrich

Anti-HNF4 antibody produced in rabbit

affinity isolated antibody

别名:

HNF-4, HNF-4-α, HNF4, HNF4A, Hepatocyte nuclear factor 4-α

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen 52 kDa

物種活性

rat, mouse, human

濃度

~1 mg/mL

技術

ELISA: 1:10000
western blot: 1:500-1:1000

NCBI登錄號

UniProt登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... HNF4A(3172)

一般說明

Anti-HNF4 Antibody detects endogenous levels of total HNF4 protein.
Hepatocyte nuclear factor 4 alpha (HNF4α) is a transcription factor, located on human chromosome 20q13.12.

免疫原

The antiserum was produced against synthesized peptide derived from human HNF4 alpha.

Immunogen Range: 280-329

生化/生理作用

Hepatocyte nuclear factor 4 alpha (HNF4α) plays an important role in the growth of liver. Mutations in HNF4α results in maturity onset diabetes of the young (MODY).

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Direct induction of hepatocyte-like cells from immortalized human bone marrow mesenchymal stem cells by overexpression of HNF4α.
Hu X, et al.
Biochemical and Biophysical Research Communications, 478(2), 791-797 (2016)
The Common p.R114W HNF4A Mutation Causes a Distinct Clinical Subtype of Monogenic Diabetes.
Laver TW, et al.
Diabetes, 65(10), 3212-3217 (2016)
Association study of genetic polymorphisms of SLC2A10 gene and type 2 diabetes in the Taiwanese population.
Lin WH, et al.
Diabetologia, 49(6), 1214-1221 (2006)

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