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Merck

SAB4300628

Sigma-Aldrich

Anti-phospho-CK2α (pThr360/Ser362) antibody produced in rabbit

affinity isolated antibody

别名:

Anti-CK2A1, Anti-CKII, Anti-CSNK2A1

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

品質等級

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

~42 kDa

物種活性

human, rat, mouse

濃度

1 mg/mL

技術

western blot: 1:500-1:1000

同型

IgG

免疫原序列

(V-P-Tp-P-Sp-P-L)

NCBI登錄號

運輸包裝

wet ice

儲存溫度

−20°C

目標翻譯後修改

phosphorylation (pThr360/pSer362)

基因資訊

human ... CTNNA1(1495)

一般說明

The antibody detects endogenous level of CK2 only when phosphorylated at thronine 360.

免疫原

Peptide sequence around phosphorylation site of threonine360/serine 362 (V-P-Tp-P-Sp-P-L), according to the protein NP_001894.2

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

標靶描述

Casein kinases are operationally defined by their preferential utilization of acidic proteins such as caseins as substrates. The alpha and alpha′ chains contain the catalytic site. Participates in Wnt signaling. CK2 phosphorylates ′Ser-392′ of p53/TP53 following UV irradiation.

外觀

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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The Journal of clinical investigation, 128(6), 2459-2472 (2018-05-08)
Many Toll-like receptors (TLRs) signal through TNF receptor-associated factor 6 (TRAF6) to activate innate immune responses. Here, we show that somatic nuclear autoantigenic sperm protein (sNASP) binds to TRAF6 to prevent TRAF6 autoubiquitination in unstimulated macrophages. Following LPS stimulation, a
Mitsutoshi Ota et al.
Arthritis & rheumatology (Hoboken, N.J.), 72(6), 931-942 (2019-12-01)
We have previously reported that the coactivation of NF-κB and STAT3 in nonimmune cells, including synovial fibroblasts, enhances the expression of NF-κB target genes and plays a role in chronic inflammation and rheumatoid arthritis (RA). This study was undertaken to

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