SAB4300498

Anti-NFKB1 (Ab-932) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-DKFZp686C01211 antibody produced in rabbit, Anti-EBP-1 antibody produced in rabbit, Anti-KBF1 antibody produced in rabbit, Anti-MGC54151 antibody produced in rabbit, Anti-nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 antibody produced in rabbit
• MDL编号: MFCD00802846
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: ~120 kDa; ~50 kDa
• 种属反应性: rat, human, mouse
• 浓度: 1 mg/mL
• 技术: immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100; western blot: 1:500-1:1000
• 同位素/亚型: IgG
• 免疫原序列: (E-T-S-F-R)
• NCBI登记号: NP_001158884.1
• UniProt登记号: P19838
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... NFKB1(4790)

说明

免疫原

Peptide sequence around aa. 930-934 (E-T-S-F-R), according to the protein NFKB1.

特点和优势

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目标描述

NF-kappa-B is a pleiotropic transcription factor which is present in almost all cell types and is involved in many biological processed such as inflammation, immunity, differentiation, cell growth, tumorigenesis and apoptosis. NF-kappa-B is a homo- or heterodimeric complex formed by the Rel-like domain-containing proteins RELA/p65, RELB, NFKB1/p105, NFKB1/p50, REL and NFKB2/p52. The dimers bind at kappa-B sites in the DNA of their target genes and the individual dimers have distinct preferences for different kappa-B sites that they can bind with distinguishable affinity and specificity. Different dimer combinations act as transcriptional activators or repressors, respectively.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable