SAB4300389

Anti-CAV1 (Ab-14) antibody produced in rabbit

affinity isolated antibody

• 别名: Anti-BSCL3 antibody produced in rabbit, Anti-CAV antibody produced in rabbit, Anti-CGL3 antibody produced in rabbit, Anti-MSTP085 antibody produced in rabbit, Anti-caveolin 1, caveolae protein, 22kDa antibody produced in rabbit
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 质量水平: 100
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: ~24 kDa
• 种属反应性: mouse, rat, human
• 浓度: 1 mg/mL
• 技术: western blot: 1:500-1:1000
• 同位素/亚型: IgG
• 免疫原序列: (H-L-Y-T-V)
• NCBI登记号: NP_001166366.1
• UniProt登记号: Q03135
• 运输: wet ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... CAV1(857)

说明

一般描述

Caveolin-1 (CAV1) is a multifunctional scaffolding protein , that has three exons. It is located on human chromosome 7q31.

免疫原

Peptide sequence around aa. 12-16 (H-L-Y-T-V), according to the protein CAV1.

生化/生理作用

Caveolin-1 is expected to play a major role in the growth and evolution of cancer. It participates in glucose metabolism. It may also participate in angiogenesis. Cav-1 helps to control the expression of glucose transporters.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

目标描述

The scaffolding protein encoded by Caveolin-1 is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 MAP kinase cascade. CAV1 and CAV2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. By using alternative initiation codons in the same reading frame, two isoforms (alpha and beta) are encoded by a single transcript from this gene.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable