SAB4200734
Anti-IL6 high affinity antibody, Mouse monoclonal
clone IL6-2A3, purified from hybridoma cell culture
别名:
Anti-B-cell stimulatory factor 2 (BSF-2), Anti-CTL differentiation factor (CDF), Anti-Hybridoma growth factor, Anti-Interferon beta-2 (IFN-beta-2), Anti-Interleukin-6
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About This Item
推荐产品
生物源
mouse
品質等級
抗體表格
purified from hybridoma cell culture
抗體產品種類
primary antibodies
無性繁殖
IL6-2A3, monoclonal
形狀
buffered aqueous solution
物種活性
human
濃度
~1.0 mg/mL
技術
ELISA: suitable
immunoblotting: 0.125-0.25 μg/mL using recombinant human IL6 expressed in HEK-293T cells
immunoprecipitation (IP): 10-20 μg/test using concentrated supernatant of human osteosarcoma MG-63 cells treated with IL1β
同型
IgG2a
UniProt登錄號
運輸包裝
dry ice
儲存溫度
−20°C
目標翻譯後修改
unmodified
基因資訊
human ... IL6(3569)
一般說明
Interleukin-6 (IL6) is a multifunctional cytokine.
免疫原
recombinant human IL6
應用
Anti-IL6 high affinity antibody, Mouse monoclonal has been used in
- immunoblotting
- immunoprecipitation
- ELISA
生化/生理作用
Interleukin-6 (IL6) plays a wide variety of important biological roles in the immune, nervous and endocrine system. It is an essential component for hybridoma growth and is found in many supplemental cloning media. IL6 regulates acute and chronic inflammatory diseases and has been proven to be an excellent target for clinical treatment against autoimmune disorders such as rheumatoid arthritis, juvenile idiopathic arthritis and Castleman′s disease. IL6 also plays a key role in the pathogenesis of multiple myeloma.
外觀
Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.
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儲存類別代碼
10 - Combustible liquids
閃點(°F)
Not applicable
閃點(°C)
Not applicable
IL-6 in autoimmune disease and chronic inflammatory proliferative disease
Cytokine & Growth Factor Reviews, 13(4-5), 357-368 (2002)
A phase 2 multicentre study of siltuximab, an anti-interleukin-6 monoclonal antibody, in patients with relapsed or refractory multiple myeloma
British Journal of Haematology, 161(3), 357-366 (2013)
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