SAB4200650

Monoclonal Anti-SH3GL1 (C-terminal) antibody produced in mouse

clone Ep2.17, purified from hybridoma cell culture

• 别名: Anti-CNSA1, Anti-EEN, Anti-SH3D2B, Anti-SH3P8
• 分類程式碼代碼: 12352203
• NACRES: NA.41

属性

• 生物源: mouse
• 品質等級: 200
• 抗體表格: purified immunoglobulin
• 抗體產品種類: primary antibodies
• 無性繁殖: Ep2.17, monoclonal
• 形狀: buffered aqueous solution
• 分子量: ~41 kDa
• 物種活性: human
• 濃度: ~1 mg/mL
• 技術: flow cytometry: 2-5 μg/test using using HeLa cells.; immunoblotting: 1-2 μg/mL using whole extracts of HeLa.
• 同型: IgG2b
• UniProt登錄號: Q99961
• 運輸包裝: dry ice
• 儲存溫度: −20°C
• 目標翻譯後修改: unmodified
• 基因資訊: human ... SH3GL1(6455)

说明

一般說明

Monoclonal Anti-SH3GL1 (C-terminal) (mouse IgG2b isotype) is derived from the hybridoma Ep2.17 produced by the fusion of mouse myeloma cells and splenocytes from BALB/c mice. SH3GL1 (SH3-domain GRB2-like 1), also known as endophilin-A2, is a member of the endophilin family of Src homology 3 (SH3) domain-containing proteins. The SH3 domain drives protein-protein interactions through binding to proline-rich ligands. The SH3GL proteins have a novel N-terminal segment, and a peculiar tissue distribution: SH3GL1 is ubiquitous, SH3GL2 located in the brain, and SH3GL3 in brain and testis.

免疫原

a synthetic peptide corresponding to a sequence at the C-terminal region of human SH3GL1

應用

Monoclonal Anti-SH3GL1 (C-terminal) antibody produced in mouse has been used in immunoblotting and flow cytometry.

生化／生理作用

SH3GL1 is involved in several brain tumors, such as glioma, where its levels were increased in proportion to the tumor progression. In cells generated from children malignant brain tumor medulloblastoma (MB), SH3GL1 expression was found to be regulated by the miRNA, miR-218.

外觀

Solution in 0.01 M phosphate buffered saline, pH 7.4, containing 15 mM sodium azide.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 儲存類別代碼: 10 - Combustible liquids
• 水污染物質分類（WGK）: WGK 1
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable