SAB4200439

Anti-EXOSC5 (N-terminal) antibody produced in rabbit

~1.0 mg/mL, affinity isolated antibody

• 别名: Anti-Exosome component 5, p12B, Anti-RRP41B, Anti-RRP46, Anti-Rrp46p, Anti-hRrp46p
• UNSPSC代码: 12352203

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: antigen ~25 kDa
• 种属反应性: human
• 浓度: ~1.0 mg/mL
• 技术: immunoprecipitation (IP): 1-2 μg using lysates of human HeLa cells.; indirect immunofluorescence: 1-2 μg/mL using human HeLa cells.; western blot: 1-2 μg/mL using whole extracts of human HEK-293T cells.
• UniProt登记号: Q9NQT4
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... EXOSC5(56915)

说明

一般描述

Exosome component 5 (EXOSC5) protein is a non-catalytic element of the RNA exosome complex in eukaryotes. The EXOSC5 gene is located on the human chromosome at 19q13.2.

特异性

Anti-EXOSC5 (N-terminal) recognizes human EXOSC5.

免疫原

peptide corresponding to the N-terminal region of human EXOSC5, conjugated to KLH. The antibody is affinity-purified using the immunizing peptide immobilized on agarose.

应用

Anti-EXOSC5 (N-terminal) antibody produced in rabbit may be used in:

• immunoblotting
• immunoprecipitation
• immunofluorescence

生化/生理作用

Exosome component 5 (EXOSC5) plays a role in the processing and degradation of RNA. This protein also plays a role in cleaving the DNA during apoptosis. EXOSC5 possesses a 3′-5′ exoribonuclease activity. Overexpression of the EXOSC5 gene is associated with several cancers such as melanoma, prostate, colorectal and lung cancer.

外形

Solution in 0.01 M phosphate buffered saline pH 7.4, containing 15 mM sodium azide.

储存及稳定性

For continuous use, store at 2-8°C for up to one month. Forextended storage freeze in working aliquots. Repeated freezing and thawing is not recommended. If slight turbidity occurs upon prolonged storage, clarify the solution by centrifugation before use. Working dilution samples should be discarded if not used within 12 hours.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 10 - Combustible liquids
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable