SAB3500033

Anti-ZBED3 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution, ab2

• 别名: Anti-Zinc finger BED-type domain containing 3
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: affinity isolated antibody
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 分子量: predicted mol wt 26 kDa
• 种属反应性: human, rat, mouse
• 技术: indirect ELISA: suitable; western blot: suitable
• NCBI登记号: NP_115743
• UniProt登记号: Q96IU2
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... ZBED3(84327)

说明

免疫原

ZBED3 antibody was raised against a 17 amino acid peptide from near the amino terminus of human ZBED3.

特点和优势

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目标描述

Axin is a key modulator of the Wnt/beta-catenin pathway and acts as a scaffold protein in phosphorylating and degrading cytoplasmic beta-catenin. ZBED3, a member of the Zinc finger BED-type domain containing superfamily, has been recently identified as an Axin-interacting protein and has been suggested to modulate the Wnt/beta-catenin signaling pathway. RNA interference (RNAi) experiments targeting ZBED3 RNA attenuated Wnt-induced beta-catenin accumulation, lymphoid enhancer binding factor-1-dependent luciferase reporter activity, and Wnt gene expression. Despite its predicted molecular weight, ZBED3 often migrates at a higher position in SDS-PAGE. This antibody is predicted to have no cross-reactivity to ZBED1 or ZBED2.

联系

The action of this antibody can be blocked using blocking peptide SBP3500033.

外形

Supplied at approx. 1 mg/mL in phosphate buffered saline containing 0.02% sodium azide.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 2
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable