跳转至内容
Merck
所有图片(1)

主要文件

SAB2900401

Sigma-Aldrich

Anti-XAF1 antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

XAF 1, XAF-1, XAF1, XIAP associated factor-1

登录查看公司和协议定价


About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

mouse, human

技术

immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable
western blot: suitable

UniProt登记号

运输

dry ice

储存温度

−20°C

靶向翻译后修饰

unmodified

基因信息

human ... XAF1(54739)

一般描述

XIAP associated factor 1 (XAF1) is a cytokine-regulated protein expressed in the cytoplasm. It contains a tumor necrosis factor receptor-associated factor (TRAF) domain. The gene encoding XAF1 is localized on human chromosome 17p13.1.

免疫原

Synthetic peptide from human XAF1/XIAP-assoicated factor 1

应用

Anti-XAF1 antibody produced in rabbit has been used in Western blotting.

生化/生理作用

XIAP associated factor 1 (XAF1) is an inhibitor of tumor growth. It has a role in restoring X-linked inhibitor of apoptosis (XIAP)-suppressed caspase activity.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

Solution in phosphate-buffered saline containing 0.02% sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

未找到合适的产品?  

试试我们的产品选型工具.

储存分类代码

10 - Combustible liquids

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

没有发现合适的版本?

如果您需要特殊版本,可通过批号或批次号查找具体证书。

已有该产品?

在文件库中查找您最近购买产品的文档。

访问文档库

X-linked inhibitor of apoptosis-associated factor 1 regulates TNF receptor 1 complex stability.
Lin B
Febs Letters (2016)
[XAF1 inhibits cell proliferation and induces apoptosis in human lung adenocarcinoma cell line A549 in vitro].
Chen D
Zhongguo Fei ai za Zhi = Chinese Journal of Lung Cancer (2014)
XAF1 is frequently methylated in human esophageal cancer.
World Journal of Gastroenterology (2012)
Andrea Lunardi et al.
Nature genetics, 45(7), 747-755 (2013-06-04)
Here we report an integrated analysis that leverages data from treatment of genetic mouse models of prostate cancer along with clinical data from patients to elucidate new mechanisms of castration resistance. We show that castration counteracts tumor progression in a
A co-clinical approach identifies mechanisms and potential therapies for androgen deprivation resistance in prostate cancer
Andrea Lunardi
Nature Genetics (2013)

我们的科学家团队拥有各种研究领域经验,包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持