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Merck
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主要文件

SAB2700012

Sigma-Aldrich

Anti-MIA3 (N-terminal) antibody produced in rabbit

affinity isolated antibody, buffered aqueous solution

别名:

ARNT, FLJ21469, FLJ39207, MIA3

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About This Item

UNSPSC代码:
12352203
NACRES:
NA.41

生物来源

rabbit

偶联物

unconjugated

抗体形式

affinity isolated antibody

抗体产品类型

primary antibodies

克隆

polyclonal

表单

buffered aqueous solution

种属反应性

human

技术

immunofluorescence: suitable
immunohistochemistry: suitable
western blot: 500-3000

NCBI登记号

UniProt登记号

运输

wet ice

储存温度

−20°C

基因信息

human ... MIA3(375056)

免疫原

Recombinant fragment corresponding to a region within amino acids 1 and 150 of MIA3 according to XP_496436

应用

Suggested starting dilutions are as follows: ICC/IF: 1:100-1:1000, IHC-P: 10 μg/mL, WB: 1:500-1:3000. Not yet tested in other applications. Optimal working dilutions should be determined experimentally by the end user.

生化/生理作用

Required for collagen VII (COL7A1) secretion by loading COL7A1 into transport carriers. May participate in cargo loading of COL7A1 at endoplasmic reticulum exit sites by binding to COPII coat subunits Sec23/24 and guiding SH3-bound COL7A1 into a growing carrier. Does not play a role in global protein secretion and is apparently specific to COL7A1 cargo loading. However, it may participate in secretion of other proteins in cells that do not secrete COL7A1.

特点和优势

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外形

0.1M Tris, 0.1M Glycine, 20% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.

免责声明

For U.S. Customers: Contains mercury; Do not place in trash - dispose according to local, state, or federal laws.
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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储存分类代码

10 - Combustible liquids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Mary S Dickinson et al.
PLoS pathogens, 15(4), e1007698-e1007698 (2019-04-04)
Chlamydia trachomatis is the most common cause of bacterial sexually transmitted infection, responsible for millions of infections each year. Despite this high prevalence, the elucidation of the molecular mechanisms of Chlamydia pathogenesis has been difficult due to limitations in genetic

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