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Merck

SAB2501381

Sigma-Aldrich

Anti-Cd28 antibody produced in goat

affinity isolated antibody, buffered aqueous solution

别名:

Anti-CH29-189K17.3, Anti-OTTMUSP00000002157, CD28 antigen, T-cell-specific surface glycoprotein CD28

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

goat

共軛

unconjugated

抗體表格

affinity isolated antibody

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

mouse, pig

技術

indirect ELISA: suitable
western blot: suitable

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

mouse ... Cd28(12487)

一般說明

Cluster of differentiation 28 (CD28) antigen is a co-stimulatory receptor expressed in naive T-cells. It contains a short cytoplasmic tail and two proline-rich motifs.

免疫原

Peptide with sequence KEKHLCHTQSSPK, from the internal region of the protein sequence according to NP_031668.3

生化/生理作用

Cluster of differentiation 28 (CD28) antigen has a role in T-cell activation, proliferation, survival and function. It modulates thymic development, peripheral homeostasis and the suppressive functions of regulatory T cells. CD28 has a role in signal transduction and is involved in activating many adaptor proteins.

特點和優勢

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

外觀

Supplied at 0.5 mg/mL in 20mM Tris (pH 7.3) and 150mM NaCl with 0.02% sodium azide and 0.5% bovine serum albumin.

免責聲明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 2

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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CD28 Deficiency Enhances Type I IFN Production by Murine Plasmacytoid Dendritic Cells.
Macal M
Journal of Immunology (2016)
CD28 Promotes Plasma Cell Survival, Sustained Antibody Responses, and BLIMP-1 Upregulation through Its Distal PYAP Proline Motif.
Rozanski CH
Journal of Immunology (2015)
Interrupting CD28 costimulation before antigen rechallenge affects CD8(+) T-cell expansion and effector functions during secondary response in mice.
Frohlich M
European Journal of Immunology (2016)
Defects in regulatory T cells due to CD28 deficiency induce a qualitative change of allogeneic immune response in chronic graft-versus-host disease.
Akieda Y
Journal of Immunology (2015)

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