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Merck
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Key Documents

SAB1406748

Sigma-Aldrich

抗-SQSTM1 小鼠抗

purified immunoglobulin, buffered aqueous solution

别名:

A170, OSIL, PDB3, ZIP3, p60, p62, p62B

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

mouse

共軛

unconjugated

抗體表格

purified immunoglobulin

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

分子量

antigen ~47.7 kDa

物種活性

human

技術

indirect immunofluorescence: suitable
western blot: 1 μg/mL

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... SQSTM1(8878)

一般說明

该基因编码一种多功能蛋白,该蛋白结合泛素并调节核因子κB(NF-kB)信号通路的激活。该蛋白作为支架/接头蛋白与TNF受体相关因子6协同作用,介导NF-κB对上游信号的激活。已经针对该基因鉴定了编码相同或不同同工型的可变剪接的转录物变体。在散发性和家族性佩吉特骨病患者中发现了该基因的突变。(由RefSeq提供)

免疫原

SQSTM1(NP_003891, 1 a.a.~ 440 a.a)全长人蛋白。

序列
MASLTVKAYLLGKEDAAREIRRFSFCCSPEPEAEAEAAAGPGPCERLLSRVAALFPALRPGGFQAHYRDEDGDLVAFSSDEELTMAMSYVKDDIFRIYIKEKKECRRDHRPPCAQEAPRNMVHPNVICDGCNGPVVGTRYKCSVCPDYDLCSVCEGKGLHRGHTKLAFPSPFGHLSEGFSHSRWLRKVKHGHFGWPGWEMGPPGNWSPRPPRAGEARPGPTAESASGPSEDPSVNFLKNVGESVAAALSPLGIEVDIDVEHGGKRSRLTPVSPESSSTEEKSSSQPSSCCSDPSKPGGNVEGATQSLAEQMRKIALESEGRPEEQMESDNCSGGDDDWTHLSSKEVDPSTGELQSLQMPESEGPSSLDPSQEGPTGLKEAALYPHLPPEADPRLIESLSQMLSMGFSDEGGWLTRLLQTKNYDIGAALDTIQYSKHPPPL

外觀

溶于pH7.4的磷酸盐缓冲盐水中的溶液

免責聲明

除非我们的产品目录或产品附带的其他公司文档另有说明,否则我们的产品仅供研究使用,不得用于任何其他目的,包括但不限于未经授权的商业用途、体外诊断用途、离体或体内治疗用途或任何类型的消费或应用于人类或动物。

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

WGK 1

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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