SAB1402484

Monoclonal Anti-HDAC4 antibody produced in mouse

clone 2B11, purified immunoglobulin, buffered aqueous solution

• 别名: HA6116, HD4, HDAC-A, HDACA, KIAA0288
• MDL编号: MFCD03455095
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: mouse
• 偶联物: unconjugated
• 抗体形式: purified immunoglobulin
• 抗体产品类型: primary antibodies
• 克隆: 2B11, monoclonal
• 表单: buffered aqueous solution
• 分子量: antigen ~36.89 kDa
• 种属反应性: human
• 技术: capture ELISA: suitable; immunofluorescence: suitable; immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable; indirect ELISA: suitable; western blot: 1-5 μg/mL
• 同位素/亚型: IgG2aκ
• NCBI登记号: NM_006037
• UniProt登记号: P56524
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... HDAC4(9759)

说明

一般描述

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. (provided by RefSeq)

免疫原

HDAC4 (NP_006028.1, 551 a.a. ~ 648 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.

Sequence
HAQAGVQVKQEPIESDEEEAEPPREVEPGQRQPSEQELLFRQQALLLEQQRIHQLRNYQASMEAAGIPVSFGGHRPLSRAQSSPASATFPVSVQEPPT

外形

Solution in phosphate buffered saline, pH 7.4

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: WGK 1
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable