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Merck
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Key Documents

SAB1300740

Sigma-Aldrich

Anti-BIRC7 (C-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

别名:

Anti-Baculoviral IAP repeat-containing protein 7, Anti-KIAP, Anti-Kidney inhibitor of apoptosis protein, Anti-ML-IAP, Melanoma inhibitor of apoptosis protein

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About This Item

分類程式碼代碼:
12352203
NACRES:
NA.41

生物源

rabbit

共軛

unconjugated

抗體表格

IgG fraction of antiserum

抗體產品種類

primary antibodies

無性繁殖

polyclonal

形狀

buffered aqueous solution

物種活性

human

技術

immunohistochemistry: 1:50-1:100
indirect ELISA: 1:1000
western blot: 1:100-1:500

NCBI登錄號

UniProt登錄號

運輸包裝

dry ice

儲存溫度

−20°C

目標翻譯後修改

unmodified

基因資訊

human ... BIRC7(79444)

一般說明

BIRC7 is a member of the family of inhibitor of apoptosis proteins (IAP) and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Two transcript variants encoding different isoforms have been found for this gene. The two isoforms have different antiapoptotic properties, with isoform alpha protecting cells from apoptosis induced by staurosporine and isoform b protecting cells from apoptosis induced by etoposide.

免疫原

BIRC7 (Q96CA5-2, 257-290)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human BIRC7.

外觀

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

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儲存類別代碼

10 - Combustible liquids

水污染物質分類(WGK)

nwg

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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