SAB1300633

Anti-PDX1 (N-term) antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-E3-binding protein, Anti-Pyruvate dehydrogenase protein X component, Dihydrolipoamide dehydrogenase-binding protein of pyruvate dehydrogenase complex
• UNSPSC代码: 12352203
• NACRES: NA.43

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: IgG fraction of antiserum
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 种属反应性: human
• 技术: immunohistochemistry: 1:50-1:100; indirect ELISA: 1:1000
• NCBI登记号: NP_000200
• UniProt登记号: P52945
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... PDX1(8050)

说明

一般描述

PDX1, located in the mitochondrial matrix, is required for anchoring dihydrolipoamide dehydrogenase (E3) to the dihydrolipoamide transacetylase (E2) core of the pyruvate dehydrogenase complexes of eukaryotes. This specific binding is essential for a functional PDH complex. Eukaryotic pyruvate dehydrogenase complexes are organized about a core consisting of the oligomeric dihydrolipoamide acetyl-transferase, around which are arranged multiple copies of pyruvate dehydrogenase, dihydrolipoamide dehydrogenase and protein X bound by noncovalent bonds. Defects in PDHX are a cause of lacticacidemia. PDX1 belongs to the 2-oxoacid dehydrogenase family and contains 1 lipoyl-binding domain.

免疫原

PDX1 (9-40)
This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PDX1.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: nwg
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable