SAB1300500

Anti-SHP2 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• 别名: Anti-PTPN11, Anti-Protein tyrosine phosphatase, non-receptor type 11 (Noonan syndrome 1), HGNC:9644, BPTP3, CFC, MGC14433, NS1, PTP-1D, PTP2C, SH-PTP2, SH-PTP3, SHP2
• UNSPSC代码: 12352203
• NACRES: NA.41

属性

• 生物来源: rabbit
• 偶联物: unconjugated
• 抗体形式: IgG fraction of antiserum
• 抗体产品类型: primary antibodies
• 克隆: polyclonal
• 表单: buffered aqueous solution
• 种属反应性: human
• 技术: indirect ELISA: 1:1000; western blot: 1:100-1:500
• NCBI登记号: NP_002825
• 运输: dry ice
• 储存温度: −20°C
• 靶向翻译后修饰: unmodified
• 基因信息: human ... SHP2(5781)

说明

一般描述

SHP2, also known as PTPN11, is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains two tandem Src homology-2 domains, which function as phospho-tyrosine binding domains and mediate the interaction of this PTP with its substrates. This PTP is widely expressed in most tissues and plays a regulatory role in various cell signaling events that are important for a diversity of cell functions, such as mitogenic activation, metabolic control, transcription regulation, and cell migration. Mutations in the gene are a cause of Noonan syndrome as well as acute myeloid leukemia.

免疫原

SHP2 (NP_002825, )
This antibody is generated from rabbits immunized with a recombinant protein encoding human SHP2.

外形

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

免责声明

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

安全信息

• 储存分类代码: 10 - Combustible liquids
• WGK: nwg
• 闪点(°F): Not applicable
• 闪点(°C): Not applicable