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Merck

S9399

Sigma-Aldrich

Staphylococcal enterotoxin A

from Staphylococcus aureus, lyophilized powder, enterotoxin

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About This Item

MDL號碼:
分類程式碼代碼:
12352200
NACRES:
NA.77

product name

金黄色葡萄球菌肠毒素A 来源于金黄色葡萄球菌,

包含

sodium phosphate buffer as balance

品質等級

成份

Protein, ~10% Lowry

存貨情形

not available in USA

雜質

Staphylococcal enterotoxin B (SEB), essentially free

溶解度

H2O: complete 1 mg/ml, clear, colorless

儲存溫度

2-8°C

一般說明

葡萄球菌肠毒素A属于葡萄球菌外毒素家族。它由金黄色葡萄球菌分泌,后者是一种革兰氏阳性菌。

應用

在TRANSIA检测试剂盒、RIDASCREEN检测试剂盒和Vidas Set 2方法的验证中,已使用来自金黄色葡萄球菌的葡萄球菌肠毒素A作为外标。用于小鼠脾细胞的体外毒素刺激。
通过给小鼠腹腔注射来自金黄色葡萄球菌的葡萄球菌肠毒素A诱导败血症。10

生化/生理作用

来自金黄色葡萄球菌的葡萄球菌肠毒素A是引起食物中毒的主要病原体。浓度低至0.5 mg/ml就足以导致恶心、呕吐、腹泻和痉挛。8 它能刺激外周血淋巴细胞的增殖,诱导干扰素的产生,对抵抗金黄色葡萄球菌感染的肠道免疫具有重要作用。9 它是T淋巴细胞的超级抗原。

包裝

包装尺寸基于蛋白质含量

相關產品

产品编号
说明
价格

象形圖

Exclamation mark

訊號詞

Warning

危險聲明

危險分類

Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

dust mask type N95 (US), Eyeshields, Gloves


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Staphylococcal enterotoxin A (SEA).
L Spero et al.
Methods in enzymology, 78(Pt A), 331-336 (1981-01-01)
Marcin Kłak et al.
Scandinavian journal of infectious diseases, 42(5), 351-358 (2010-01-27)
Haemostatic balance shifts towards pro-coagulation during infection. Plasminogen, a key molecule of fibrinolysis, may play an important role in the pathogenesis of staphylococcal infections. In the present study, we assessed the impact of inhibition of plasminogen activation by tranexamic acid
Determination of staphylococcal enterotoxins in cheese by immunoenzyme assays
<BIG>Jankovic V, et al.</BIG>
Archives of Biological Sciences, 64, 1449-1454 (2012)
Dong Zhang et al.
Oncoimmunology, 9(1), 1744921-1744921 (2020-04-22)
T cell immunoglobulin and mucin domain-3 (TIM-3) is an immune checkpoint that regulates normal immune responses but can be exploited by tumor cells to evade immune surveillance. TIM-3 is primarily expressed on immune cells, particularly on dysfunctional and exhausted T
Targeting of key pathogenic factors from gram-positive bacteria by the soluble ectodomain of the scavenger-like lymphocyte receptor CD6
<BIG>Martinez F, et al.</BIG>
The Journal of Infectious Diseases, 209, 1077-1086 (2013)

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