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Merck

S8524

Sigma-Aldrich

N-Succinyl-Ile-Ile-Trp-7-amido-4-methylcoumarin

protease substrate

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About This Item

经验公式(希尔记法):
C37H45N5O8
分子量:
687.78
MDL號碼:
分類程式碼代碼:
12352204
PubChem物質ID:

形狀

solid

儲存溫度

−20°C

SMILES 字串

CC[C@H](C)[C@H](NC(=O)CCC(O)=O)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)Nc3ccc4C(C)=CC(=O)Oc4c3

InChI

1S/C37H45N5O8/c1-6-20(3)33(41-30(43)14-15-31(44)45)37(49)42-34(21(4)7-2)36(48)40-28(17-23-19-38-27-11-9-8-10-26(23)27)35(47)39-24-12-13-25-22(5)16-32(46)50-29(25)18-24/h8-13,16,18-21,28,33-34,38H,6-7,14-15,17H2,1-5H3,(H,39,47)(H,40,48)(H,41,43)(H,42,49)(H,44,45)/t20-,21-,28-,33-,34-/m0/s1

InChI 密鑰

DIQQFBVJYYDILY-DFXXCKAUSA-N

儲存類別代碼

11 - Combustible Solids

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)


分析证书(COA)

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G C Kundu et al.
Life sciences, 50(13), 965-970 (1992-01-01)
An enzyme partially purified from bovine lung membranes appears to be endothelin converting enzyme (ECE). This enzyme specifically cleaves big endothelin-1 (big ET-1) at the proper site, between Trp21 and Val22, with maximum activity at pH 7.5 and with a
G C Kundu et al.
International journal of peptide and protein research, 42(1), 64-67 (1993-07-01)
The metal ion of endothelin-converting enzyme (ECE) was investigated by inhibiting the enzyme with ethylenediaminetetraacetic acid (EDTA) and restoring activity by adding divalent metal salts in quantities less than the concentration of EDTA. Under these conditions, only metal ions that
Salvatore de Stefano et al.
Natural product letters, 16(3), 207-211 (2002-06-07)
A novel metabolite related to the previously identified compound 3-O-methylfunicone (1) was isolated from the fungus Penicillium pinophilum and its structure elucidated by spectral analysis as 3-O-methyl-5, 6-epoxyfunicone (2).
Endothelin converting enzyme of porcine lung.
L J Murphy et al.
Biochemical Society transactions, 21(1), 27S-27S (1993-02-01)

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