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Merck
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文件

S6647

Sigma-Aldrich

[D-Pro4, D-Trp7,9, Nle11]-Substance P Fragment 4-11

≥95% (HPLC)

别名:

D-Pro-Gln-Gln-D-Trp-Phe-D-Trp-Leu-Nle-NH2

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About This Item

经验公式（希尔记法）:
C58H77N13O10
CAS号:
89430-34-2
分子量:
1116.31
MDL號碼:
MFCD00133834
分類程式碼代碼:
12352200
PubChem物質ID:
24899718

化驗

≥95% (HPLC)

UniProt登錄號

P20366

儲存溫度

−20°C

SMILES 字串

CCCCC(NC(=O)C(CC(C)C)NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(Cc3ccccc3)NC(=O)C(Cc4c[nH]c5ccccc45)NC(=O)C(CCC(N)=O)NC(=O)C(CCC(N)=O)NC(=O)C6CCCN6)C(N)=O

InChI

1S/C58H77N13O10/c1-4-5-18-41(51(61)74)65-55(78)45(27-33(2)3)68-57(80)48(30-36-32-64-40-20-12-10-17-38(36)40)71-56(79)46(28-34-14-7-6-8-15-34)69-58(81)47(29-35-31-63-39-19-11-9-16-37(35)39)70-54(77)44(23-25-50(60)73)67-53(76)43(22-24-49(59)72)66-52(75)42-21-13-26-62-42/h6-12,14-17,19-20,31-33,41-48,62-64H,4-5,13,18,21-30H2,1-3H3,(H2,59,72)(H2,60,73)(H2,61,74)(H,65,78)(H,66,75)(H,67,76)(H,68,80)(H,69,81)(H,70,77)(H,71,79)

InChI 密鑰

OFDJVNRFKDPBKR-UHFFFAOYSA-N

基因資訊

human ... TAC1(6863)

生化／生理作用

A potent substance P antagonist

儲存類別代碼

11 - Combustible Solids

水污染物質分類（WGK）

WGK 3

閃點（°F）

Not applicable

閃點（°C）

Not applicable

個人防護裝備

Eyeshields, Gloves, type N95 (US)

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Synthesis of substance P antagonists: [D-Pro4, D-Trp7,9,Nle11]-substance P(4-11).
G Köller et al.
Die Pharmazie, 39(1), 65-67 (1984-01-01)
G Bredy-Dobreva et al.
Acta physiologica et pharmacologica Bulgarica, 15(3), 10-15 (1989-01-01)
The effects of a new analogue of substance P (SP-A) and its interaction with substance P (SP) were studied in vitro isolated preparations from rabbit renal arteries and rat renal and pulmonary arteries. SP-A in did not affect the resting
Ruofan Wang et al.
Cell, 184(1), 106-119 (2020-12-18)
The Coronaviridae are a family of viruses that cause disease in humans ranging from mild respiratory infection to potentially lethal acute respiratory distress syndrome. Finding host factors common to multiple coronaviruses could facilitate the development of therapies to combat current

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