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Merck

S4881

Sigma-Aldrich

葡萄球菌肠毒素B 来源于金黄色葡萄球菌

别名:

SEB, 肠毒素B,葡萄球菌

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About This Item

CAS号:
MDL號碼:
分類程式碼代碼:
12352202
NACRES:
NA.25

包含

sodium phosphate buffer as balance

品質等級

成份

Protein, ~25% Lowry

存貨情形

not available in USA

雜質

Staphylococcal enterotoxin A (SEA), essentially free

應用

metabolomics
vitamins, nutraceuticals, and natural products

儲存溫度

2-8°C

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應用

与 MHC II 类分子和 T 细胞受体(TCR)的特异性 Vβ 区结合的葡萄球菌肠毒素 B(SEB),可导致单核细胞/巨噬细胞和 T 淋巴细胞的激活,可用作超抗原和免疫系统激活剂。 SEB 可用作 SEB 检测系统开发中的参考材料。

生化/生理作用

T 淋巴细胞的超抗原。 与主要组织相容性复合体(MHC)抗原和 CD28 结合的免疫系统激活剂。

包裝

包装尺寸基于蛋白质含量。

相關產品

产品编号
说明
价格

象形圖

Skull and crossbones

訊號詞

Danger

危險分類

Acute Tox. 1 Dermal - Acute Tox. 1 Inhalation - Acute Tox. 1 Oral - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

標靶器官

Respiratory system

儲存類別代碼

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

水污染物質分類(WGK)

WGK 3

閃點(°F)

Not applicable

閃點(°C)

Not applicable


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Clarifying the mechanism of superantigen toxicity.
John D Fraser
PLoS biology, 9(9), e1001145-e1001145 (2011-09-21)
Oliver G Weingart et al.
Sensors (Basel, Switzerland), 12(2), 2324-2339 (2012-03-23)
Prevalent incidents support the notion that toxins, produced by bacteria, fungi, plants or animals are increasingly responsible for food poisoning or intoxication. Owing to their high toxicity some toxins are also regarded as potential biological warfare agents. Accordingly, control, detection
Winnie Bergstedt et al.
PloS one, 5(6), e11277-e11277 (2010-07-02)
Tuberculin is still the only available skin test reagent for the diagnosis of mycobacterial infection. The product has a remarkable sensitivity, but poor specificity. Previous studies, including two human phase I clinical trials, have indicated that rdESAT-6 has a potential
Bacterial superantigens
Proft, T. and Fraser, J.D.
Clinical and Experimental Immunology, 133, 299-299 (2008)
Iria Gomez-Tourino et al.
Nature communications, 8(1), 1792-1792 (2017-11-28)
Defects in T cell receptor (TCR) repertoire are proposed to predispose to autoimmunity. Here we show, by analyzing >2 × 10

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