S3321

SUN B8155

≥97% (HPLC), solid

• 别名: 5-[1-[(2-Aminophenyl)imino]ethyl]-1,6-dihydroxy-4-methyl-2(1H)-pyridinone
• 经验公式（希尔记法）: C₁₄H₁₅N₃O₃
• CAS号: 345893-91-6
• 分子量: 273.29
• MDL號碼: MFCD08276926
• 分類程式碼代碼: 51111800
• PubChem物質ID: 24724606

属性

• 化驗: ≥97% (HPLC)
• 形狀: solid
• 溶解度: DMSO: ≥5 mg/mL
• 儲存溫度: 2-8°C
• SMILES 字串: CC1=CC(=O)N(O)C(O)=C1\C(C)=N\c2ccccc2N
• InChI: 1S/C14H15N3O3/c1-8-7-12(18)17(20)14(19)13(8)9(2)16-11-6-4-3-5-10(11)15/h3-7,19-20H,15H2,1-2H3/b16-9+
• InChI 密鑰: SGJLINMLDNLWOS-CXUHLZMHSA-N

说明

應用

SUN B8155 may be used to study calcitonin-mediated cell signaling.

生化／生理作用

SUN B8155 is a pyridine derivative that mimics calcitonin, a peptide hormone crucial in maintain the bone homeostasis. It stimulated the formation of cAMP in T47D and UMR106-06 cells expressing calcitonin receptor.

SUN B8155 is a nonpeptide calcitonin receptor agonist.

安全信息

• 象形圖: GHS06
• 訊號詞: Danger
• 危險聲明: H301
• 防範說明: P301 + P310
• 危險分類: Acute Tox. 3 Oral
• 儲存類別代碼: 11 - Combustible Solids
• 水污染物質分類（WGK）: WGK 3
• 閃點（°F）: Not applicable
• 閃點（°C）: Not applicable
• 個人防護裝備: dust mask type N95 (US), Eyeshields, Faceshields, Gloves