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物種活性
human
包裝
kit of 96 wells (12 strips x 8 wells)
技術
ELISA: suitable
assay range
inter-assay cv: <10%
intra-assay cv: <12%
檢測方法
colorimetric
運輸包裝
wet ice
儲存溫度
−20°C
基因資訊
human ... SSSCA1(10534)
一般說明
The SSSCA1 (Sjoegren syndrome/scleroderma autoantigen 1) gene codes for a cell cycle inhibitor, also called as p27. The SSSCA1 gene is mapped to human chromosome 11q13.1.
The antibody pair provided in this kit recognizes human SSSCA1.
應用
请参考Protocol了解详情。
生化／生理作用
Sjoegren Syndrome Autoantigen 1 is an important cyclin-dependent kinase complexes inhibitor and prevents the G1 to S phase transition during cell cycle. It is regulated by ubiquitin-proteasome. The Sjoegren Syndrome Autoantigen 1 gene expression is downregulated in cancer and indicates poor prognosis.
訊號詞
Warning
危險聲明
防範說明
危險分類
Met. Corr. 1
儲存類別代碼
8A - Combustible corrosive hazardous materials
閃點（°F）
Not applicable
閃點（°C）
Not applicable
Loss of 3p26. 3 is an independent prognostic factor in patients with oral squamous cell carcinoma.
Uchida K, et al.
Oncology Reports, 26(2), 463-469 (2011)
Expression of CRM1 in human gliomas and its significance in p27 expression and clinical prognosis.
Shen A, et al.
Neurosurgery, 65(1), 153-160 (2009)
Subcellular localization of p27 and prostate cancer recurrence: automated digital microscopy analysis of tissue microarrays.
Ananthanarayanan V, et al.
Human Pathology, 42(6), 873-881 (2011)
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