种属反应性
human
包装
kit of 96 wells (12 strips x 8 wells)
技术
ELISA: suitable
输入
sample type plasma
sample type cell culture supernatant(s)
sample type serum
assay range
inter-assay cv: <12%
intra-assay cv: <10%
sensitivity: 80 pg/mL
standard curve range: 81.92-20000 pg/mL
检测方法
colorimetric
运输
wet ice
储存温度
−20°C
基因信息
human ... IL1F7(27178)
一般描述
The IL1F7 ELISA kit provides for the quantitative measurement of IL-37 in cell culture supernatants, plasma and serum.
The interleukin 37 (IL1F7) gene is expressed in several tissues such as thymus, lymph nodes, testis, uterus, placenta, bone marrow and lungs. The gene IL1F7 exists in five isoforms IL1F7a-e. The IL1F7 gene is mapped to human chromosome 2q14.1.
The interleukin 37 (IL1F7) gene is expressed in several tissues such as thymus, lymph nodes, testis, uterus, placenta, bone marrow and lungs. The gene IL1F7 exists in five isoforms IL1F7a-e. The IL1F7 gene is mapped to human chromosome 2q14.1.
应用
请参考Protocol了解详情。
生化/生理作用
Interleukin 37 (IL1F7) suppresses the innate immune response. The IL1F7 gene expression is associated with many inflammatory disorders including dermatosis, hepatopathy, digestive system disorders, autoimmune diseases, ischemia/reperfusion injury and other metabolic diseases. The anti-inflammatory action of IL1F7 might affect tumor inflammation mechanism.
其他说明
A sample Certificate of Analysis is available for this product.
Please type the word sample in the text box provided for lot number.
Please type the word sample in the text box provided for lot number.
警示用语：
Warning
危险声明
预防措施声明
危险分类
Met. Corr. 1
储存分类代码
8A - Combustible corrosive hazardous materials
闪点(°F)
Not applicable
闪点(°C)
Not applicable
Interleukin-37 expression and its potential role in oral leukoplakia and oral squamous cell carcinoma.
Lin L, et al.
Scientific Reports, 6, 26757-26757 (2016)
Associations of the Interleukin?1 Gene Locus Polymorphisms with Risk to Hip and Knee Osteoarthritis: Gender and Subpopulation Differences.
Kaarvatn M H, et al.
Human immunology, 77(2), 151-161 (2013)
The effects of selective hematopoietic expression of human IL-37 on systemic inflammation and atherosclerosis in LDLr-deficient mice.
Hoeke G, et al.
International Journal of Molecular Sciences, 18(8), 1672-1672 (2017)
Javier Rodríguez-Carrio et al.
Frontiers in immunology, 9, 2351-2351 (2018-10-30)
Introduction: B-cell activation is pivotal in rheumatoid arthritis (RA) pathogenesis and represents a relevant therapeutic target. The main aim of this study was to characterize the profiles of B-cell factors and their decoy receptors in RA and evaluate their clinical
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